Further investigation of the
discriminative stimulus properties of MDA

by
Glennon RA, Young R.
Department of Psychology,
Carleton University,
Ottawa, Ontario.
Pharmacol Biochem Behav 1984 Apr;20(4):501-5


ABSTRACT

Rats trained to discriminate either (+)-amphetamine or (+/-)-MDA from saline in a two-lever drug discrimination task, were used to study the stimulus effects of MDA and its two optical isomers. Amphetamine-stimulus generalization occurred to S(+)-MDA, but not to its enantiomer R(-)-MDA. This, coupled with our earlier finding of DOM-stimulus generalization to R(-)-MDA but not to S(+)-MDA, suggests that the stimulus effects of S(+)-MDA are predominantly amphetamine-like while those of R(-)-MDA are more DOM-like. Thus, animals trained to discriminate racemic MDA from saline can apparently recognize members of both classes of agents.

History
MDMA/MDE
Controversies
MDA: structure
MDA (from PIHKAL)
Protect and survive
MDA: optical isomers
MDA dual stimulus effects
Fine axon terminal damage
MDA-assisted psychotherapy
MDA, serotonin terminal loss and Prozac


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