Fatality Due To Combined Use of the Designer Drugs
MDMA and PMA: A Distribution Study
Dams R, De Letter EA, Mortier KA, Cordonnier JA,
Lambert WE, Piette MH, Van Calenbergh S, De Leenheer AP.
Laboratorium voor Toxicologie, Universiteit Gent,
Harelbekestraat 72, B-9000 Gent, Belgium.
J Anal Toxicol. 2003 Jul-Aug;27(5):318-22.
ABSTRACTWe present a fatal case involving the combined ingestion of amphetamine, 3,4-methylenedioxymethylamphetamine, 3,4-methylenedioxyamphetamine, and paramethoxyamphetamine. Various postmortem specimens (e.g., several blood samples, urine, and tissue samples) were analyzed to study the distribution of the compounds and their metabolites in the human body. Quantitation took place using liquid chromatography-sonic spray ionization-mass spectrometry after pretreatment with a liquid-liquid extraction. The medico-legal findings were compatible with a disseminated intravascular coagulation induced by hyperthermia caused by the simultaneous intake of the amphetamine analogues.PMA
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